OBJECTIVE To develop a core outcome set for trials on the treatment of hyperemesis gravidarum (HG). DESIGN Identification of outcomes is followed by a modified Delphi survey combined with a consensus development meeting and a consultation round. SETTING An international web-based survey combined with a consensus development meeting. POPULATION Stakeholders including researchers; women with lived experience of HG and their families; obstetric health professionals; and other health professionals. METHODS We used systematic review, semi-structured patient interviews, closed group sessions, and Steering Committee input to identify potential core outcomes. We conducted two web-based survey rounds, followed by a face-to-face consensus development meeting and a web-based consultation round. MAIN OUTCOME MEASURES A core outcome set for research on HG. RESULTS Fifty-six potential outcomes were identified. The modified Delphi process was completed by 125 stakeholders, the consensus development meeting by 20 stakeholders, and the consultation round by 96 stakeholders. Consensus was reached in ten domains on 24 outcomes nausea; vomiting; inability to tolerate oral fluids or food; dehydration; weight difference; electrolyte imbalance; intravenous fluid treatment; use of medication for hyperemesis gravidarum; hospital treatment; treatment compliance; patient satisfaction; daily functioning; maternal physical or mental or emotional wellbeing; short- and long-term adverse effects of treatment; maternal death; pregnancy complications; considering or actually terminating a wanted pregnancy; preterm birth; small for gestational age; congenital anomalies; neonatal morbidity and offspring death). CONCLUSIONS This core outcome set will help standardise outcome reporting in HG trials. TWEETABLE ABSTRACT A core outcome set for treatment of hyperemesis gravidarum in order to create high-quality evidence. © 2020 Royal College of Obstetricians and Gynaecologists.BACKGROUND Achieving activity participation goals is a key factor in quality of life (QOL) for people with aphasia (PWA), but expressing participation goals can be difficult for many of them. Proxy reports by caregivers may not accurately reflect the interests and participation goals of PWA, and discrepancies in these goals between PWA and their caregivers may affect QOL, based on the assumption that caregivers' awareness of their loved ones' unique participation goals may be important to increasing PWA activity participation. AIMS To examine everyday activities valued by PWA using the Life Interests and Values (LIV) Cards; to measure congruence between PWA and their caregivers on life participation goals; and to measure how congruence of PWA-caregiver participation goals related to QOL. https://www.selleckchem.com/products/shp099-dihydrochloride.html METHODS &amp; PROCEDURES A convenience sample of 25 PWA completed the LIV Card assessment and the Stroke Aphasia Quality of Life Scale-39 to assess participation goals and QOL. Participation goals were also evaluated with respected within four activity domains (home and community activities, creative and relaxing activities, physical activities, and social activities). Results indicated that agreement between PWA and their caregiver proxies on PWA's most desired activities was less then 50%. However, the level of agreement between caregivers and proxies on participation goals was not significantly related to QOL in this sample. What are the potential or actual clinical implications of this work? PWA have a variety of participation goals that can be integrated into intervention plans to be carried out with clinicians, caregivers and family members. The use of proxy respondents when determining participation goals should be reduced as much as possible to support self-determination for PWA. Use of the LIV Cards, a picture-based sorting-task assessment, reduces the need for proxy responders and guesswork about the specific participation goals of PWA. © 2020 Royal College of Speech and Language Therapists.Photosynthetic bacteria (PSB) technology is a promising method for biomass, protein, pigments, and other value-added substances generation from wastewater. However, the above bioresources production efficiency is relatively low. In this work, a static magnetic field (SMF) was used to promote bioresources production. Results showed that SMF had positive effects on value-added substances production. With 0.35 Tesla (T) SMF, the PSB biomass, protein, carotenoids, and bacteriochlorophyll concentration were promoted by 31.1%, 22.6%, 56.7%, and 73.1% compared with the control group, respectively. Biomass yield finally reached 0.58&nbsp;g biomass/g COD removal, which was promoted by 37.1%. The doubling time was shortened by 37.9% in 0.35&nbsp;T group, showing that SMF can promote cell growth. With 0.35&nbsp;T SMF, the intracellular NADH dehydrogenase and ATP synthase activities concentration increased by 23.4% and 29.1%, respectively, thus increased the ATP content by 38.0%. Succinic dehydrogenase activity concentration greatly increased by 609.0% at 48&nbsp;hr, which potentially accelerated the tricarboxylic acid&nbsp;cycle and COD degradation as well as enhanced biomass production. PRACTITIONER POINTS SMF promoted PSB bioresource production during wastewater treatment processing. Biomass, protein, carotenoids, and Bchl concentration were promoted by 31.1%, 22.6%, 56.7%, and 73.1%, respectively. PSB yield of 0.35 T group was promoted by 37.1% compared with the control group. SDH concentration of 0.35 T was promoted by 609.0% compared with the control group. Increased NADH and ATP synthase activity concentration by SMF enhanced energy metabolism. © 2020 Water Environment Federation.Antimony(III) borates with a stereochemical active lone pair remained unknown, although the first antimony borate was reported more than twenty years ago. Now, the first antimony(III) borate in a closed system is successfully synthesized, namely SbB3 O6 . Remarkably, SbB3 O6 not only exhibits an exceptional linear optical response, that is, birefringence of Δn=0.290 at the wavelength of 546?nm, which is the largest among borates, but also has a strong nonlinear optical response of 3.5 times larger than the benchmark KH2 PO4 , exceeding those of most borates. Theoretical calculations reveal that the coexistence of strong linear and nonlinear optical responses in SbB3 O6 should be attributable to the synergistic effect of π-conjugated B-O anionic groups and Sb3+ with stereochemically active lone pair. This work provides a new class of optical bi-functional materials with potential prospects in integrated optical devices. © 2020 Wiley-VCH Verlag GmbH &amp; Co. KGaA, Weinheim.